Arthritis

Brief Overview: Arthritis is a broad term for conditions that cause joint inflammation, pain, stiffness, and decreased mobility. There are more than 100 types, but the most common in adults 60+ are osteoarthritis (OA)—a “wear-and-tear” condition of cartilage breakdown—and rheumatoid arthritis (RA)—an autoimmune condition that attacks joints. Arthritis is a leading cause of disability in older adults.

Prevalence:

  • Over 54 million U.S. adults have some form of arthritis.
  • Prevalence increases with age: nearly 50% of adults 65+ report diagnosed arthritis.
  • Women are more commonly affected than men.
  • Osteoarthritis is the most prevalent type.

Etiology:

  • Osteoarthritis: Degeneration of joint cartilage and underlying bone due to aging, overuse, or injury.
  • Rheumatoid Arthritis: Autoimmune reaction where the immune system attacks joint lining.
  • Other forms: Gout (uric acid crystal deposits), psoriatic arthritis, lupus-related arthritis.

Risk Factors:

  • Age (risk increases significantly after 50).
  • Female sex (higher prevalence of RA and OA in women).
  • Family history/genetics.
  • Joint injury or overuse.
  • Obesity (increases joint load, especially knees and hips).
  • Autoimmune diseases (RA, lupus).

Commonly Associated Conditions:

  • Chronic pain syndromes.
  • Depression/anxiety (due to chronic pain and disability).
  • Metabolic syndrome and obesity.

Common Medications:

  • For osteoarthritis:
    • Acetaminophen (mild pain).
    • NSAIDs (ibuprofen, naproxen, topical diclofenac).
    • Corticosteroid injections.
  • For RA and autoimmune types:
    • DMARDs (methotrexate, sulfasalazine).
    • Biologics (adalimumab, etanercept).
    • Corticosteroids (short-term use).
  • Adjuncts: Topical analgesics, antidepressants for neuropathic pain, muscle relaxants.

Common Labs, Imaging, and Tests:

  • Labs (especially for RA): Rheumatoid factor (RF), anti-CCP antibodies, ESR, CRP.
  • Imaging:
    • X-rays (joint space narrowing, osteophytes).
    • MRI (cartilage, ligaments, early inflammation).
    • Ultrasound (synovitis, joint fluid).
  • Joint aspiration (for gout or infection evaluation).

Common Symptoms:

  • Joint pain and tenderness.
  • Stiffness, especially in the morning or after rest.
  • Swelling around joints.
  • Reduced range of motion.
  • Crepitus (grating sound with joint movement).
  • In RA: symmetrical joint involvement, fatigue, low-grade fever.

Common Treatments:

  • Conservative: Physical therapy, exercise, weight management, assistive devices.
  • Medications (see above)
  • Injections: Corticosteroids, hyaluronic acid (OA).
  • Surgical options: Joint replacement (hip, knee), arthroscopy in select cases.

Physical Findings:

  • Tender or swollen joints.
  • Limited range of motion.
  • Bony enlargements (e.g., Heberden’s nodes in OA).
  • Warmth and redness (in inflammatory arthritis).
  • Joint deformities (e.g., ulnar deviation in RA).

 

Potential Complications and Contraindications:

  • Progressive joint damage and disability.
  • Loss of independence in daily activities.
  • Increased fall risk due to stiffness and weakness.
  • Medication side effects: GI bleeding (NSAIDs), liver/lung toxicity (methotrexate), infection risk (biologics).
  • Cardiovascular disease risk in RA.

General Health and Lifestyle Guidance:

  • Maintain healthy weight to reduce stress on joints.
  • Stay physically active with low-impact exercise (walking, swimming, tai chi). Ask your healthcare provider what exercises are recommended for you.
  • Practice range-of-motion and strengthening exercises.
  • Use assistive devices (canes, braces, shoe inserts) as needed.
  • Apply heat or cold packs for symptom relief.
  • Balanced diet: anti-inflammatory foods (fish, fruits, vegetables, whole grains). Ask your healthcare provider if any specific dietary modifications are recommended for you.
  • Avoid smoking and excess alcohol (worsen inflammation and medication side effects).

Suggested Questions to Ask Patients:

  • Which joints are most affected, and how long have you had symptoms?
  • Do you experience stiffness in the morning, and how long does it last?
  • How does pain impact your ability to perform daily activities?
  • Have you tried medications or therapy, and how effective were they?
  • Have you noticed fatigue, fever, or weight changes (suggesting systemic arthritis)?
  • Have you had any falls or balance issues related to joint pain?
  • What coping strategies or support systems do you use?

Suggested Talking Points:

  • Arthritis is very common as we age, but there are many treatment options to manage pain and maintain function.
  • Staying active—even with gentle movement—helps keep joints flexible and reduces stiffness.
  • Weight management can significantly reduce stress on your joints, especially the knees and hips.
  • For autoimmune types like rheumatoid arthritis, early treatment with the right medications can help try to prevent long-term damage.
  • Let your healthcare provider know if you have side effects from medications, or if your pain changes suddenly.
  • You are not alone—support groups and community programs are available to help you manage arthritis.

Sources:

This content was created with the assistance of AI. Any AI-generated content was reviewed by a Nurse Practitioner.