Chronic Pelvic Pain - Females

Condition: Chronic Pelvic Pain - Females

Brief Overview: According to UpToDate, “While there is no consensus on the definition of CPP, it is generally defined as non-cyclic pain perceived to be in the pelvic area that has persisted for at least three to six months, or longer, and is unrelated to pregnancy.”

Prevalence: According to UpToDate, “Globally, female CPP has been reported to affect 6 to 25 percent of reproductive-age women.”

Etiology: There are many possible etiologies for chronic pelvic pain in females. Some of these are:

  • Gynecologic causes: endometriosis, adhesions, prior PID, adenomyosis, fibroids, ovarian cysts, pelvic congestion.
  • Urologic causes: interstitial cystitis / bladder pain syndrome
  • GI causes: irritable bowel syndrome, inflammatory bowel disease, constipation, celiac disease
  • Musculoskeletal: pelvic floor myofascial pain, fibromyalgia
  • Psychosocial: history of trauma/abuse, anxiety, depression
  • Some cancers/malignancies

Risk Factors:

  • History of pelvic inflammatory disease or STIs
  • Endometriosis or prior gynecologic conditions
  • Pelvic floor dysfunction
  • Recurrent UTIs or IC/BPS
  • IBS or other GI disorders
  • Sexual trauma or adverse childhood experiences

Commonly Associated Conditions:

  • Endometriosis
  • Interstitial cystitis / bladder pain syndrome
  • IBS, IBD
  • Celiac Disease
  • Pelvic floor dysfunction
  • Vulvodynia, dyspareunia
  • Fibromyalgia

Common Medications: There isn’t a medications specifically for CPP. Medication will depend on the underlying etiology and symptoms.

Common Labs, Imaging, and Tests:

  • Urinalysis, STI testing, pregnancy testing
  • GI studies
  • Imaging: Ultrasound, MRI, CT
  • Laparoscopy

Common Symptoms:

  • Non-cyclic pelvic pain
  • Urinary symptoms
  • Dyspareunia
  • GI symptoms
  • Decreased quality of life
  • Depression, anxiety, increased stress

Common Treatments:

  • Lifestyle & behavioral strategies: gentle stretching, heat therapy, bladder/bowel irritant avoidance, stress management.
  • Pelvic floor physical therapy: addressing muscle tension, trigger points, and pelvic floor dysfunction.
  • Pharmacologic therapy: NSAIDs, hormonal therapy, neuropathic agents, relaxants.
  • Minimally invasive procedures: trigger point injections, nerve blocks.
  • Multidisciplinary care: gynecology, urology, GI, behavioral health, pain management.
  • Cognitive behavioral therapy (CBT) or trauma-informed therapy if indicated.
  • Laparoscopy may be indicated

Physical Findings:

  • Pelvic floor muscle tenderness
  • Pain with bimanual exam
  • Suprapubic or adnexal tenderness
  • Normal or minimal imaging findings possible despite significant symptoms

Potential Complications and Contraindications:

  • Sexual dysfunction
  • Anxiety, depression, reduced quality of life
  • Bladder or bowel dysfunction
  • Chronic pain sensitization
  • Misdiagnosis or delayed diagnosis

General Health and Lifestyle Guidance:

  • Encourage regular follow-up with all healthcare providers, including gynecology, urology, or pelvic pain specialists.
  • Promote pelvic floor relaxation strategies.
  • Adequate hydration and balanced diet to minimize bladder/GI triggers.
  • Stress management and mental health support.
  • Warm compresses, heat therapy, and gentle movement may be helpful.

Suggested Questions to Ask Patients:

  • How long have you had pelvic pain, and how would you describe it?
  • Does pain occur in relation to your menstrual cycle?
  • Are urinary or bowel symptoms present?
  • Have you ever had pelvic infections or surgery?
  • Does intercourse worsen your symptoms?
  • Have you tried any physical therapy or medications?
  • How is this pain affecting your quality of life?

Suggested Talking Points:

  • Chronic pelvic pain is common and often involves multiple factors.
  • Your treatment plan may involve a combination of approaches.
  • Pelvic floor therapy and pain management can make a big difference.
  • You may have several specialists to create the best plan for you.
  • Always ask your healthcare provider for specific advice on when to call to report symptoms, and when to seek urgent/emergency care.  

Sources:

This resource is for educational purposes only and is not a substitute for professional medical advice. The patient should always follow your healthcare provider’s instructions.

This content was created with the assistance of AI. Any AI-generated content was reviewed by a Nurse Practitioner