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Erectile Dysfunction (ED): A Brief Guide

What ED Means

  • Erectile Dysfunction (ED) refers to difficulty in getting or keeping an erection firm enough for sexual intercourse.
  • It’s fairly common, and its likelihood increases with age and in the presence of certain health conditions.

How Erections Normally Work

  1. Nerves release signals (nitric oxide) when you’re aroused.
  2. These signals relax smooth muscle and open blood flow to the penis.
  3. The inflow of blood fills erectile tissue, and veins compress to trap it — maintaining rigidity.
  4. After sexual activity or when stimulation stops, blood exits and the penis returns to a flaccid state.

In ED, one or more of these steps is impaired (nerve signaling, blood flow, muscle relaxation, venous trapping).

Common Causes & Risk Factors

Type

Examples / Contributors

Vascular / Blood Flow Issues

Atherosclerosis, high blood pressure, high cholesterol, diabetes

Neurological

Nerve damage, pelvic surgery, spinal injury, multiple sclerosis

Hormonal / Endocrine

Low testosterone, thyroid conditions

Medications / Substances

Some blood pressure meds, antidepressants, smoking, alcohol, recreational drugs

Psychological

Stress, anxiety, depression, performance pressure

Anatomical / Structural Issues

Peyronie’s disease (scar tissue), penile curvature, venous leak

Signs & Symptoms You May Notice

  • Difficulty getting an erection
  • Difficulty sustaining the erection during sexual activity
  • Loss of spontaneous erections (e.g. morning erections)
  • Decreased sexual desire
  • Emotional distress, reduced confidence, or relationship strain

Diagnosing ED

A healthcare provider will often:

  1. Review your medical history, symptoms, and medications
  2. Ask about sexual and psychological factors
  3. Perform a physical exam (genitals, pulses, nerves)
  4. Order lab tests — e.g. blood sugar, cholesterol, testosterone
  5. Possibly do additional testing (ultrasound, nocturnal erection tests, etc.) to assess blood flow or nerve function

What You Can Do to Help Yourself

  • Address any underlying conditions: control diabetes, hypertension, high cholesterol
  • Maintain a healthy weight, exercise regularly, stop smoking
  • Limit alcohol, avoid illicit drugs
  • Manage stress, anxiety, or mood issues
  • Get adequate sleep— poor sleep can worsen hormonal and vascular health
  • Talk openly with your partner or a counselor
  • Ask your doctor whether medication side effects might be contributing

Treatment Options

Option

What It Does

Considerations

Oral medications (PDE5 inhibitors, e.g. sildenafil, tadalafil)

Improve blood flow by enhancing nitric oxide signaling

Works best when the nerves and vessels are still reasonably intact

Injected medications / intraurethral therapies

Directly stimulate erection via local agents

More invasive; may cause discomfort or priapism

Vacuum erection devices

Mechanical method to engorge penis

Can be effective though less spontaneous

Penile implants / prostheses

Surgically inserted devices that allow controllable erection

Higher cost / more invasive, but very effective in many cases

Shockwave therapy, stem cell / regenerative therapies

Emerging alternatives aiming to restore vascular function

Still considered experimental in many cases

Psychosexual therapy / counseling

Address anxiety, relationship or performance issues that contribute

Often used alongside physical treatments

When to Seek Medical Help

If you notice:

  • Sudden onset of ED
  • ED with other symptoms like chest pain, shortness of breath, or dizziness (could signal heart disease)
  • Painful erections or scarring / deformity of the penis
  • Signs of low testosterone (low libido, fatigue, muscle loss)
  • Medication side effects
  • Always ask your healthcare provider for specific advice on when to call to report symptoms, and when to seek urgent/emergency care.  

Key Takeaways

  • ED is a symptom, not a disease — it often signals blood vessel, nerve, or hormonal issues
  • Many effective treatments exist; your doctor can help you find the best fit
  • Lifestyle, mindset, and partner communication can play significant roles
  • Early evaluation is better — waiting may allow underlying issues to worsen
This handout is for educational purposes only and is not a substitute for professional medical advice. Always follow your healthcare provider’s instructions.

Sources:

This content was created with the assistance of AI. Any AI-generated content was reviewed by a Nurse Practitioner